NPB Cesium Space Experiment

Neutral Particle Beam (NPB) weapons systems are planned to perform the ballistic missile defense functions of nuclear weapon/decoy discrimination and warhead kill at appropriate energy levels and ion currents. Negatively charged ions are produced in a specialized ion source and focused into a high quality particle beam. NPB linear accelerators accelerate and steer the negatively charged ions using electric and magnetic fields. After acceleration and steering the neutralizer system strips away extra electrons from ions to form the electrically neutral particle beam. The neutral beam then travels through space to the target unaffected by the Earth's magnetic fields. Continuing technological advances have greatly reduced the size and weight of NPB accelerator systems. Ion current production has been enhanced by over 100 percent with the intermittent addition of cesium at the NPB ion source device. This increase in current is essential to attain the most light weight, compact NPB platforms and minimize expensive launch costs. Addition of cesium into the ion source has been identified by the NPB community as the highest priority risk reduction space experiment necessary prior to planned NPB accelerator experiments and later weapons systems. The NPB Cesium Space Experiment is planned to successfully demonstrate controlled cesium introduction and vaporization into a simulated ion source chamber. Microgravity effects on the cesium deposition will be studied as will the effects of small amounts of cesium on high voltage accelerator components that might be susceptible to electrical insulator break downs. The experiment design will simulate as closely as possible the environment, physical and operational characteristics of the actual NPB ion source

The green-leaved variant of Eucalyptus largiflorens: a story involving hybridization and observant local people

Eucalyptus largiflorens (Black Box) is the most common tree in the Chowilla anabranch system on the Murray River floodplain. It typically has dull, glaucous, grey-green leaves. Occasional trees with smaller, glossy green leaves (Green Box) occur scattered amongst the Black Box. In areas with increasing salinity, they usually appear much healthier than adjacent, normal Black Box trees. Green Box plants are intermediate between normal Eucalyptus largiflorens plants and Eucalyptus gracilis plants in many morphological and allozyme characters, strongly suggesting that they are hybrids between those species. Green Box plants tolerate salinity better and use water more conservatively than normal Black Box plants, traits that they have probably inherited from Eucalyptus gracilis. In 1994, the Botanic Gardens of Adelaide used tissue culture and micropropagation to produce nearly 9,000 cloned Green Box plants which were planted out on Riverland floodplains. Since the 1990s, the high cost of producing clonal plants has meant that no further such plantings have occurred. Because Green Box plants can be a considerable distance from the nearest plants of one putative parent (Eucalyptus gracilis), more detailed studies could contribute to the existing work on such phantom hybrids

\u3ci\u3eHippodamia Variegata\u3c/i\u3e (Goeze) (Coleoptera: Coccinellidae) Detected in Michigan Soybean Fields

Since its initial detection near Montreal, Canada in 1984, the variegated lady beetle Hippodamia variegata (Goeze) (Coleoptera:Coccinellidae) has spread throughout the northeastern United States. In 2005, this immigrant Old World species was detected in Michigan for the first time. Twenty-nine adults were found in soybean fields in 4 counties: Ingham, Gratiot, Kalamazoo, and Saginaw.The first individuals were found in Gratiot County on 22 June 2005; we continued to detect individuals until 18 Aug 2005 (2 individuals collected in Saginaw Co.) when sampling ended. Prior to this study, H. variegata had not been known to prey on the soybean aphid, Aphis glycines Matsumura (Homoptera: Aphididae). The establishment of soybean aphid throughout the north-central U.S. may aid the spread of H. variegata throughout the region

Characterisation of nicotine receptors on human peripheral blood mononuclear cells (PBMC)

“The original publication is available at www.springerlink.com”. Copyright Springer. DOI: 10.1007/s00011-008-8171-xAim and objective: The aim of the work was to characterise the nAChRs on human PBMC. Method: PBMC were isolated from human blood buffy coats provided by the blood transfusion service and were used for radioligand binding studies with [3H]-nicotine. RT-PCR experiments were used to determine nAChR subunit expression while immunoblotting experiments were used to confirm that nAChR subunits identified by RT-PCR were translated into protein. Results: Binding studies suggested the presence of one binding site for (-)- nicotine on human peripheral blood lymphocytes. Competition studies showed that only (-)- nicotine, epibatidine and α-bungarotoxin, displaced radiolabelled nicotine from cells. RT-PCR studies demonstrated mRNA for α4, α5, α7, β1 and β2 nAChRs subunits in PBMC. Expression of mRNA for the a5 subunit of nAChR was observed in all lymphocyte samples tested. In contrast, the expression pattern of mRNAs for α4, α7, β1, and β2 mRNAs subunits of nAChRs, varied between samples. Western blot analysis showed that protein for α4, α5, and α7 and β2 nAChR subunits was expressed in most, but not all of the PBMC samples tested but some of the bands obtained were faint. Conclusion: The results obtained suggest that human PBMC contain nAChRs containing α4β2, α4β2α5, and/or α7 subunits.Peer reviewe

The evolution of the self-lensing binary KOI-3278: evidence of extra energy sources during CE evolution

Post-common-envelope binaries (PCEBs) have been frequently used to observationally constrain models of close-compact-binary evolution, in particular common-envelope (CE) evolution. However, recent surveys have detected PCEBs consisting of a white dwarf (WD) exclusively with an M dwarf companion. Thus, we have been essentially blind with respect to PCEBs with more massive companions. Recently, the second PCEB consisting of a WD and a G-type companion, the spectacularly self-lensing binary KOI-3278, has been identified. This system is different from typical PCEBs not only because of the G-type companion, but also because of its long orbital period. Here we investigate whether the existence of KOI-3278 provides new observational constraints on theories of CE evolution. We reconstruct its evolutionary history and predict its future using BSE, clarifying the proper use of the binding energy parameter in this code. We find that a small amount of recombination energy, or any other source of extra energy, is required to reconstruct the evolutionary history of KOI-3278. Using BSE we derive progenitor system parameters of M1,i = 2.450 Msun, M2,i = 1.034 Msun, and Porb,i ~ 1300 d. We also find that in ~9 Gyr the system will go through a second CE phase leaving behind a double WD, consisting of a C/O WD and a He WD with masses of 0.636 Msun and 0.332 Msun, respectively. After IK Peg, KOI-3278 is the second PCEB that clearly requires an extra source of energy, beyond that of orbital energy, to contribute to the CE ejection. Both systems are special in that they have long orbital periods and massive secondaries. This may also indicate that the CE efficiency increases with secondary mass.Comment: Accepted for publication in A&A Letters, 4 pages, 2 figure

Cotton spinning to climbing gear: practical aspects of design evolution in Lancashire and the North West of England

This article looks at the role of path dependency in the design of outdoor clothing and equipment, from the perspective of changing and overlapping industrial clusters in Lancashire and Sheffield, from the 1960s. It demonstrates that, unlike the fashion market, design in mountaineering clothing and equipment was originally based heavily upon functionality and hence on user innovation. It shows that skills and knowledge which evolved during the industrial revolution, in both industrial areas, were vitally important to the development of internationally competitive mountaineering equipment firms. It was, however, the way in which these sources of knowledge were combined with sporting expertise that contributed to the design of innovative functional products. In addition, fundamental changes occurred in the relationship between manufacturers and their customers and these were vital to the success of this process, marking a departure from past practice

Infrared Dark Cloud Cores in the SCUBA Legacy Catalogue

We present an investigation of candidate Infrared Dark Cloud cores as identified by Simon et al. (2006) located within the SCUBA Legacy Catalogue. After applying a uniform noise cut to the Catalogue data we identify 154 Infrared Dark Cloud cores that were detected at 850um and 51 cores that were not. We derive column densities for each core from their 8um extinction and find that the IRDCs detected at 850um have higher column densities (a mean of 1.7x10^22 cm-2) compared to those cores not detected at 850um (a mean of 1.0x10^22 cm-2). Combined with sensitivity estimates, we suggest that the cores not detected at 850um are low mass, low column density and low temperature cores that are below the sensitivity limit of SCUBA at 850um. For a subsample of the cores detected at 850um those contained within the MIPSGAL area) we find that two thirds are associated with 24um sources. Cores not associated with 24um emission are either ``starless'' IRDC cores that perhaps have yet to form stars, or contain low mass YSOs below the MIPSGAL detection limit. We see that those ``starless'' IRDC cores and the IRDC cores associated with 24um emission are drawn from the same column density population and are of similar mass. If we then assume the cores without 24um embedded sources are at an earlier evolutionary stage to cores with embedded objects we derive a statistical lifetime for the quiescent phase of a few 10^3-10^4 years. Finally, we make conservative predictions for the number of observed IRDCs that will be observed by the Apex Telescope Galactic Plane Survey (ATLASGAL), the Herschel Infrared Galactic Plane Survey (Hi-GAL), the JCMT Galactic Plane Survey (JPS) and the SCUBA-2 ``All Sky'' Survey (SASSy).Comment: 18 pages, 3 tables, 10 figure

A model for the study of ligand binding to the ribosomal RNA helix h44.

Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation. Techniques such as selective chemical modification, fluorescence labeling and mutations are cumbersome for the whole ribosome but readily applicable to model RNAs, which are readily crystallized and often give rise to higher resolution crystal structures suitable for detailed analysis of ligand-RNA interactions. Here, we have investigated the HX RNA construct which contains two adjacent ligand binding regions of helix h44 in 16S ribosomal RNA. High-resolution crystal structure analysis confirmed that the HX RNA is a faithful structural model of the ribosomal target. Solution studies showed that HX RNA carrying a fluorescent 2-aminopurine modification provides a model system that can be used to monitor ligand binding to both the ribosomal decoding site and, through an indirect effect, the hygromycin B interaction region

Do agonistic behaviours bias baited remote underwater video surveys of fish?

Marine environments require monitoring to determine the effects of impacts such as climate change, coastal development and pollution and also to assess the effectiveness of conservation measures. Marine protected areas (MPAs) are being established globally and require periodic monitoring to determine whether their objectives are being met. Baited underwater video systems are becoming a popular method for monitoring change within protected fish populations, because they are less damaging to habitats than bottom trawling and allow for more statistical powerful comparisons to determine spatial and temporal patterns in the relative abundances, lengths and biomass of demersal and pelagic fishes. However, much remains uncertain about how interactions between the fish and bait and between the fish themselves affect the results obtained. Agonistic behaviours are frequently observed around the bait of the camera and potentially bias fish density estimates by altering the number and size classes seen at cameras. Here we counted the number of agonistic behaviours between pink snappers (Pagrus auratus), the size of fish involved and whether the fish left the field of view following such behaviours. The study consisted of 20 baited underwater video deployments inside a New Zealand marine reserve and 20 in adjacent open areas. We observed a significant relationship between the peak number of fish observed at the camera and the total number of agonistic behaviours, as well as the number of both aggressor and subordinate fish leaving the camera field of view following interactions. The slope of the latter relationship and thus the absolute numbers of fish leaving were higher for subordinate fish. As subordinates were significantly smaller than aggressors, the apparent size frequency distribution is likely skewed away from smaller size classes. The staying time of the fish and thus the maximum number of fish present at the camera will be reduced by agonistic behaviours and the absolute magnitude of this effect appears to be greater at high fish densities. Our results suggest that an overall effect of these phenomena is to underestimate the differences in abundance between MPAs and open areas, but also to overestimate differences in average size